Putative hAPN receptor binding sites in SARS_CoV spike protein.
Identifieur interne : 005E95 ( Main/Exploration ); précédent : 005E94; suivant : 005E96Putative hAPN receptor binding sites in SARS_CoV spike protein.
Auteurs : Xiao-Jing Yu [République populaire de Chine] ; Cheng Luo ; Jian-Cheng Lin ; Pei Hao ; You-Yu He ; Zong-Ming Guo ; Lei Qin ; Jiong Su ; Bo-Shu Liu ; Yin Huang ; Peng Nan ; Chuan-Song Li ; Bin Xiong ; Xiao-Min Luo ; Guo-Ping Zhao ; Gang Pei ; Kai-Xian Chen ; Xu Shen ; Jian-Hua Shen ; Jian-Ping Zou ; Wei-Zhong He ; Tie-Liu Shi ; Yang Zhong ; Hua-Liang Jiang ; Yi-Xue LiSource :
- Acta pharmacologica Sinica [ 1671-4083 ] ; 2003.
Descripteurs français
- KwdFr :
- Alignement de séquences, Biologie informatique, Cartographie d'interactions entre protéines, Domaine catalytique, Données de séquences moléculaires, Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (), Glycoprotéines membranaires (génétique), Glycoprotéines membranaires (métabolisme), Humains, Liaison aux protéines, Protéines de l'enveloppe virale (), Protéines de l'enveloppe virale (génétique), Protéines de l'enveloppe virale (métabolisme), Sites de fixation, Structure tertiaire des protéines, Syndrome respiratoire aigu sévère (virologie), Séquence d'acides aminés, Virus du SRAS (), Virus du SRAS (génétique).
- MESH :
- génétique : Glycoprotéines membranaires, Protéines de l'enveloppe virale, Virus du SRAS.
- métabolisme : Glycoprotéines membranaires, Protéines de l'enveloppe virale.
- virologie : Syndrome respiratoire aigu sévère.
- Alignement de séquences, Biologie informatique, Cartographie d'interactions entre protéines, Domaine catalytique, Données de séquences moléculaires, Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires, Humains, Liaison aux protéines, Protéines de l'enveloppe virale, Sites de fixation, Structure tertiaire des protéines, Séquence d'acides aminés, Virus du SRAS.
English descriptors
- KwdEn :
- Amino Acid Sequence, Binding Sites, CD13 Antigens (chemistry), CD13 Antigens (genetics), CD13 Antigens (metabolism), Catalytic Domain, Computational Biology, Humans, Membrane Glycoproteins (chemistry), Membrane Glycoproteins (genetics), Membrane Glycoproteins (metabolism), Molecular Sequence Data, Protein Binding, Protein Interaction Mapping, Protein Structure, Tertiary, SARS Virus (chemistry), SARS Virus (genetics), Sequence Alignment, Severe Acute Respiratory Syndrome (virology), Spike Glycoprotein, Coronavirus, Viral Envelope Proteins (chemistry), Viral Envelope Proteins (genetics), Viral Envelope Proteins (metabolism).
- MESH :
- chemical , chemistry : CD13 Antigens, Membrane Glycoproteins, Viral Envelope Proteins.
- chemical , genetics : CD13 Antigens, Membrane Glycoproteins, Viral Envelope Proteins.
- chemical , metabolism : CD13 Antigens, Membrane Glycoproteins, Viral Envelope Proteins.
- chemistry : SARS Virus.
- genetics : SARS Virus.
- virology : Severe Acute Respiratory Syndrome.
- Amino Acid Sequence, Binding Sites, Catalytic Domain, Computational Biology, Humans, Molecular Sequence Data, Protein Binding, Protein Interaction Mapping, Protein Structure, Tertiary, Sequence Alignment, Spike Glycoprotein, Coronavirus.
Abstract
To obtain the information of ligand-receptor binding between the S protein of SARS-CoV and CD13, identify the possible interacting domains or motifs related to binding sites, and provide clues for studying the functions of SARS proteins and designing anti-SARS drugs and vaccines.
PubMed: 12791172
Affiliations:
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Le document en format XML
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last="Zou">Jian-Ping Zou</name></author><author><name sortKey="He, Wei Zhong" sort="He, Wei Zhong" uniqKey="He W" first="Wei-Zhong" last="He">Wei-Zhong He</name></author><author><name sortKey="Shi, Tie Liu" sort="Shi, Tie Liu" uniqKey="Shi T" first="Tie-Liu" last="Shi">Tie-Liu Shi</name></author><author><name sortKey="Zhong, Yang" sort="Zhong, Yang" uniqKey="Zhong Y" first="Yang" last="Zhong">Yang Zhong</name></author><author><name sortKey="Jiang, Hua Liang" sort="Jiang, Hua Liang" uniqKey="Jiang H" first="Hua-Liang" last="Jiang">Hua-Liang Jiang</name></author><author><name sortKey="Li, Yi Xue" sort="Li, Yi Xue" uniqKey="Li Y" first="Yi-Xue" last="Li">Yi-Xue Li</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2003">2003</date><idno type="RBID">pubmed:12791172</idno><idno type="pmid">12791172</idno><idno type="wicri:Area/PubMed/Corpus">003351</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" 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wicri:level="1"><nlm:affiliation>Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031</wicri:regionArea><wicri:noRegion>Shanghai 200031</wicri:noRegion></affiliation></author><author><name sortKey="Luo, Cheng" sort="Luo, Cheng" uniqKey="Luo C" first="Cheng" last="Luo">Cheng Luo</name></author><author><name sortKey="Lin, Jian Cheng" sort="Lin, Jian Cheng" uniqKey="Lin J" first="Jian-Cheng" last="Lin">Jian-Cheng Lin</name></author><author><name sortKey="Hao, Pei" sort="Hao, Pei" uniqKey="Hao P" first="Pei" last="Hao">Pei Hao</name></author><author><name sortKey="He, You Yu" sort="He, You Yu" uniqKey="He Y" first="You-Yu" last="He">You-Yu He</name></author><author><name sortKey="Guo, Zong Ming" sort="Guo, Zong Ming" uniqKey="Guo Z" first="Zong-Ming" last="Guo">Zong-Ming Guo</name></author><author><name sortKey="Qin, Lei" sort="Qin, Lei" uniqKey="Qin L" first="Lei" last="Qin">Lei Qin</name></author><author><name sortKey="Su, Jiong" sort="Su, Jiong" uniqKey="Su J" first="Jiong" last="Su">Jiong Su</name></author><author><name sortKey="Liu, Bo Shu" sort="Liu, Bo Shu" uniqKey="Liu B" first="Bo-Shu" last="Liu">Bo-Shu Liu</name></author><author><name sortKey="Huang, Yin" sort="Huang, Yin" uniqKey="Huang Y" first="Yin" last="Huang">Yin Huang</name></author><author><name sortKey="Nan, Peng" sort="Nan, Peng" uniqKey="Nan P" first="Peng" last="Nan">Peng Nan</name></author><author><name sortKey="Li, Chuan Song" sort="Li, Chuan Song" uniqKey="Li C" first="Chuan-Song" last="Li">Chuan-Song Li</name></author><author><name sortKey="Xiong, Bin" sort="Xiong, Bin" uniqKey="Xiong B" first="Bin" last="Xiong">Bin Xiong</name></author><author><name sortKey="Luo, Xiao Min" sort="Luo, Xiao Min" uniqKey="Luo X" first="Xiao-Min" last="Luo">Xiao-Min Luo</name></author><author><name sortKey="Zhao, Guo Ping" sort="Zhao, Guo Ping" uniqKey="Zhao G" first="Guo-Ping" last="Zhao">Guo-Ping Zhao</name></author><author><name sortKey="Pei, Gang" sort="Pei, Gang" uniqKey="Pei G" first="Gang" last="Pei">Gang Pei</name></author><author><name sortKey="Chen, Kai Xian" sort="Chen, Kai Xian" uniqKey="Chen K" first="Kai-Xian" last="Chen">Kai-Xian Chen</name></author><author><name sortKey="Shen, Xu" sort="Shen, Xu" uniqKey="Shen X" first="Xu" last="Shen">Xu Shen</name></author><author><name sortKey="Shen, Jian Hua" sort="Shen, Jian Hua" uniqKey="Shen J" first="Jian-Hua" last="Shen">Jian-Hua Shen</name></author><author><name sortKey="Zou, Jian Ping" sort="Zou, Jian Ping" uniqKey="Zou J" first="Jian-Ping" last="Zou">Jian-Ping Zou</name></author><author><name sortKey="He, Wei Zhong" sort="He, Wei Zhong" uniqKey="He W" first="Wei-Zhong" last="He">Wei-Zhong He</name></author><author><name sortKey="Shi, Tie Liu" sort="Shi, Tie Liu" uniqKey="Shi T" first="Tie-Liu" last="Shi">Tie-Liu Shi</name></author><author><name sortKey="Zhong, Yang" sort="Zhong, Yang" uniqKey="Zhong Y" first="Yang" last="Zhong">Yang Zhong</name></author><author><name sortKey="Jiang, Hua Liang" sort="Jiang, Hua Liang" uniqKey="Jiang H" first="Hua-Liang" last="Jiang">Hua-Liang Jiang</name></author><author><name sortKey="Li, Yi Xue" sort="Li, Yi Xue" uniqKey="Li Y" first="Yi-Xue" last="Li">Yi-Xue Li</name></author></analytic><series><title level="j">Acta pharmacologica Sinica</title><idno type="ISSN">1671-4083</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence</term><term>Binding Sites</term><term>CD13 Antigens (chemistry)</term><term>CD13 Antigens (genetics)</term><term>CD13 Antigens (metabolism)</term><term>Catalytic Domain</term><term>Computational Biology</term><term>Humans</term><term>Membrane Glycoproteins (chemistry)</term><term>Membrane Glycoproteins (genetics)</term><term>Membrane Glycoproteins (metabolism)</term><term>Molecular Sequence Data</term><term>Protein Binding</term><term>Protein Interaction Mapping</term><term>Protein Structure, Tertiary</term><term>SARS Virus (chemistry)</term><term>SARS Virus (genetics)</term><term>Sequence Alignment</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Spike Glycoprotein, Coronavirus</term><term>Viral Envelope Proteins (chemistry)</term><term>Viral Envelope Proteins (genetics)</term><term>Viral Envelope Proteins (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Alignement de séquences</term><term>Biologie informatique</term><term>Cartographie d'interactions entre protéines</term><term>Domaine catalytique</term><term>Données de séquences moléculaires</term><term>Glycoprotéine de spicule des coronavirus</term><term>Glycoprotéines membranaires ()</term><term>Glycoprotéines membranaires (génétique)</term><term>Glycoprotéines membranaires (métabolisme)</term><term>Humains</term><term>Liaison aux protéines</term><term>Protéines de l'enveloppe virale ()</term><term>Protéines de l'enveloppe virale (génétique)</term><term>Protéines de l'enveloppe virale (métabolisme)</term><term>Sites de fixation</term><term>Structure tertiaire des protéines</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Séquence d'acides aminés</term><term>Virus du SRAS ()</term><term>Virus du SRAS (génétique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>CD13 Antigens</term><term>Membrane Glycoproteins</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>CD13 Antigens</term><term>Membrane Glycoproteins</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>CD13 Antigens</term><term>Membrane Glycoproteins</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Glycoprotéines membranaires</term><term>Protéines de l'enveloppe virale</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Glycoprotéines membranaires</term><term>Protéines de l'enveloppe virale</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term><term>Binding Sites</term><term>Catalytic Domain</term><term>Computational Biology</term><term>Humans</term><term>Molecular Sequence Data</term><term>Protein Binding</term><term>Protein Interaction Mapping</term><term>Protein Structure, Tertiary</term><term>Sequence Alignment</term><term>Spike Glycoprotein, Coronavirus</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Alignement de séquences</term><term>Biologie informatique</term><term>Cartographie d'interactions entre protéines</term><term>Domaine catalytique</term><term>Données de séquences moléculaires</term><term>Glycoprotéine de spicule des coronavirus</term><term>Glycoprotéines membranaires</term><term>Humains</term><term>Liaison aux protéines</term><term>Protéines de l'enveloppe virale</term><term>Sites de fixation</term><term>Structure tertiaire des protéines</term><term>Séquence d'acides aminés</term><term>Virus du SRAS</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To obtain the information of ligand-receptor binding between the S protein of SARS-CoV and CD13, identify the possible interacting domains or motifs related to binding sites, and provide clues for studying the functions of SARS proteins and designing anti-SARS drugs and vaccines.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><noCountry><name sortKey="Chen, Kai Xian" sort="Chen, Kai Xian" uniqKey="Chen K" first="Kai-Xian" last="Chen">Kai-Xian Chen</name><name sortKey="Guo, Zong Ming" sort="Guo, Zong Ming" uniqKey="Guo Z" first="Zong-Ming" last="Guo">Zong-Ming Guo</name><name sortKey="Hao, Pei" sort="Hao, Pei" uniqKey="Hao P" first="Pei" last="Hao">Pei Hao</name><name sortKey="He, Wei Zhong" sort="He, Wei Zhong" uniqKey="He W" first="Wei-Zhong" last="He">Wei-Zhong He</name><name sortKey="He, You Yu" sort="He, You Yu" uniqKey="He Y" first="You-Yu" last="He">You-Yu He</name><name sortKey="Huang, Yin" sort="Huang, Yin" uniqKey="Huang Y" first="Yin" last="Huang">Yin Huang</name><name sortKey="Jiang, Hua Liang" sort="Jiang, Hua Liang" uniqKey="Jiang H" first="Hua-Liang" last="Jiang">Hua-Liang Jiang</name><name sortKey="Li, Chuan Song" sort="Li, Chuan Song" uniqKey="Li C" first="Chuan-Song" last="Li">Chuan-Song Li</name><name sortKey="Li, Yi Xue" sort="Li, Yi Xue" uniqKey="Li Y" first="Yi-Xue" last="Li">Yi-Xue Li</name><name sortKey="Lin, Jian Cheng" sort="Lin, Jian Cheng" uniqKey="Lin J" first="Jian-Cheng" last="Lin">Jian-Cheng Lin</name><name sortKey="Liu, Bo Shu" sort="Liu, Bo Shu" uniqKey="Liu B" first="Bo-Shu" last="Liu">Bo-Shu Liu</name><name sortKey="Luo, Cheng" sort="Luo, Cheng" uniqKey="Luo C" first="Cheng" last="Luo">Cheng Luo</name><name sortKey="Luo, Xiao Min" sort="Luo, Xiao Min" uniqKey="Luo X" first="Xiao-Min" last="Luo">Xiao-Min Luo</name><name sortKey="Nan, Peng" sort="Nan, Peng" uniqKey="Nan P" first="Peng" last="Nan">Peng Nan</name><name sortKey="Pei, Gang" sort="Pei, Gang" uniqKey="Pei G" first="Gang" last="Pei">Gang Pei</name><name sortKey="Qin, Lei" sort="Qin, Lei" uniqKey="Qin L" first="Lei" last="Qin">Lei Qin</name><name sortKey="Shen, Jian Hua" sort="Shen, Jian Hua" uniqKey="Shen J" first="Jian-Hua" last="Shen">Jian-Hua Shen</name><name sortKey="Shen, Xu" sort="Shen, Xu" uniqKey="Shen X" first="Xu" last="Shen">Xu Shen</name><name sortKey="Shi, Tie Liu" sort="Shi, Tie Liu" uniqKey="Shi T" first="Tie-Liu" last="Shi">Tie-Liu Shi</name><name sortKey="Su, Jiong" sort="Su, Jiong" uniqKey="Su J" first="Jiong" last="Su">Jiong Su</name><name sortKey="Xiong, Bin" sort="Xiong, Bin" uniqKey="Xiong B" first="Bin" last="Xiong">Bin Xiong</name><name sortKey="Zhao, Guo Ping" sort="Zhao, Guo Ping" uniqKey="Zhao G" first="Guo-Ping" last="Zhao">Guo-Ping Zhao</name><name sortKey="Zhong, Yang" sort="Zhong, Yang" uniqKey="Zhong Y" first="Yang" last="Zhong">Yang Zhong</name><name sortKey="Zou, Jian Ping" sort="Zou, Jian Ping" uniqKey="Zou J" first="Jian-Ping" last="Zou">Jian-Ping Zou</name></noCountry><country name="République populaire de Chine"><noRegion><name 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